Annual Report | MedicOath

7,000+

diseases with no approved treatment

£1.1T

pharma industry annual revenue

97%

of R&D goes to profitable diseases

1,842

AI hypotheses generated

£2

cost per discovery run

patents filed — every discovery free

1. The Scale of Neglect

Of ~10,000 known human diseases, fewer than 500 have approved treatments. The pharmaceutical industry directs 97% of R&D toward diseases affecting wealthy populations. The remaining 3% covers thousands of diseases affecting billions.

2. The Most Neglected Diseases

NomaNeglect: 97/100

Deaths: 140,000/yrFunding: £0

3 hypotheses generated

ProgeriaNeglect: 96/100

Deaths: ~100/yrFunding: <£790K/yr globally

1 hypothesis generated

Fibrodysplasia Ossificans ProgressivaNeglect: 97/100

Deaths: All affectedFunding: £0

In queue

Buruli UlcerNeglect: 95/100

Deaths: Minimal (disfigurement)Funding: <£4M/yr

1 hypothesis generated

Visceral LeishmaniasisNeglect: 94/100

Deaths: 30,000/yrFunding: <£39M/yr

5 hypotheses, 1 in pre-clinical

3. Corporate Accountability

PfizerRevenue: £46B

Spent on Noma, Progeria, Buruli Ulcer:

£0

Johnson & JohnsonRevenue: £67B

Spent on Sleeping Sickness, Tay-Sachs:

£0

RocheRevenue: £50B

Spent on Chagas, ME/CFS:

£0

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Pharma Exposed